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Complementary functions of ATM and H2AX in development and suppression of genomic instability
Upon DNA damage, histone H2AX is phosphorylated by ataxia-telangiectasia mutated (ATM) and other phosphoinositide 3-kinase-related protein kinases. To elucidate further the potential overlapping and unique functions of ATM and H2AX, we asked whether they have synergistic functions in the development...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453730/ https://ncbi.nlm.nih.gov/pubmed/18599436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803520105 |
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