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Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
Nonhomologous DNA end-joining (NHEJ) is a major pathway of DNA double-strand break (DSB) repair in mammalian cells, and it functions to join both specifically programmed DSBs that occur in the context of V(D)J recombination during early lymphocyte development as well as general DSBs that occur in al...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838633/ https://ncbi.nlm.nih.gov/pubmed/17360556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611734104 |
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