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Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells

Nonhomologous DNA end-joining (NHEJ) is a major pathway of DNA double-strand break (DSB) repair in mammalian cells, and it functions to join both specifically programmed DSBs that occur in the context of V(D)J recombination during early lymphocyte development as well as general DSBs that occur in al...

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Detaylı Bibliyografya
Asıl Yazarlar: Zha, Shan, Alt, Frederick W., Cheng, Hwei-Ling, Brush, James W., Li, Gang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838633/
https://ncbi.nlm.nih.gov/pubmed/17360556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611734104
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