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Defective DNA Repair and Increased Genomic Instability in Artemis-deficient Murine Cells
In developing lymphocytes, the recombination activating gene endonuclease cleaves DNA between V, D, or J coding and recombination signal (RS) sequences to form hairpin coding and blunt RS ends, which are fused to form coding and RS joins. Nonhomologous end joining (NHEJ) factors repair DNA double st...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193825/ https://ncbi.nlm.nih.gov/pubmed/12615897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021891 |
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