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Defective DNA Repair and Increased Genomic Instability in Artemis-deficient Murine Cells
In developing lymphocytes, the recombination activating gene endonuclease cleaves DNA between V, D, or J coding and recombination signal (RS) sequences to form hairpin coding and blunt RS ends, which are fused to form coding and RS joins. Nonhomologous end joining (NHEJ) factors repair DNA double st...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193825/ https://ncbi.nlm.nih.gov/pubmed/12615897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021891 |
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