Control of Sister Chromatid Recombination by Histone H2AX

SUMMARY: Histone H2AX has a role in suppressing genomic instability and cancer. However, the mechanisms by which it performs these functions are poorly understood. After DNA breakage, H2AX is phosphorylated on serine 139 in chromatin near the break. We show here that H2AX serine 139 enforces efficie...

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Detaylı Bibliyografya
Asıl Yazarlar: Xie, Anyong, Puget, Nadine, Shim, Inbo, Odate, Shobu, Jarzyna, Ingeborga, Bassing, Craig H., Alt, Frederick W., Scully, Ralph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991138/
https://ncbi.nlm.nih.gov/pubmed/15610743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2004.12.007
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