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Control of Sister Chromatid Recombination by Histone H2AX

SUMMARY: Histone H2AX has a role in suppressing genomic instability and cancer. However, the mechanisms by which it performs these functions are poorly understood. After DNA breakage, H2AX is phosphorylated on serine 139 in chromatin near the break. We show here that H2AX serine 139 enforces efficie...

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Detalhes bibliográficos
Main Authors: Xie, Anyong, Puget, Nadine, Shim, Inbo, Odate, Shobu, Jarzyna, Ingeborga, Bassing, Craig H., Alt, Frederick W., Scully, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991138/
https://ncbi.nlm.nih.gov/pubmed/15610743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2004.12.007
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