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H2AX post-translational modifications in the ionizing radiation response and homologous recombination
Histone H2AX phosphorylation on a C-terminal serine residue to form “γ-H2AX” is a critical early event in the chromatin response to chromosomal DNA double strand breaks in eukaryotes. In mammalian cells, γ-H2AX is formed when H2AX is phosphorylated on serine 139 by ATM or by other DNA damage respons...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980696/ https://ncbi.nlm.nih.gov/pubmed/20703100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.17.12884 |
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