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Complementary functions of ATM and H2AX in development and suppression of genomic instability

Upon DNA damage, histone H2AX is phosphorylated by ataxia-telangiectasia mutated (ATM) and other phosphoinositide 3-kinase-related protein kinases. To elucidate further the potential overlapping and unique functions of ATM and H2AX, we asked whether they have synergistic functions in the development...

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Detalhes bibliográficos
Main Authors: Zha, Shan, Sekiguchi, JoAnn, Brush, James W., Bassing, Craig H., Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453730/
https://ncbi.nlm.nih.gov/pubmed/18599436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803520105
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