Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression

Ataxia-telangiectasia (A-T) mutated (ATM) kinase signals all three cell cycle checkpoints after DNA double-stranded break (DSB) damage. H2AX, NBS1, and p53 are substrates of ATM kinase and are involved in ATM-dependent DNA damage responses. We show here that H2AX is dispensable for the activation of...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kang, Jian, Ferguson, David, Song, Hoseok, Bassing, Craig, Eckersdorff, Mark, Alt, Frederick W., Xu, Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2005
Assuntos:	Signal Transduction
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC543410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15632067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.2.661-670.2005
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