Wordt geladen...

Inhibition of ZAP-70 Kinase Activity via an Analog-sensitive Allele Blocks T Cell Receptor and CD28 Superagonist Signaling

ZAP-70 is a cytoplasmic protein tyrosine kinase that is required for T cell antigen receptor (TCR) signaling. Both mice and humans deficient in ZAP-70 fail to develop functional T cells, thus demonstrating its necessity for T cell development and function. There is currently no highly specific, cell...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Levin, Susan E., Zhang, Chao, Kadlecek, Theresa A., Shokat, Kevan M., Weiss, Arthur
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397475/
https://ncbi.nlm.nih.gov/pubmed/18378687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709000200
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!