Cardiac Restricted Overexpression of Kinase-dead Mammalian Target of Rapamycin (mTOR) Mutant Impairs the mTOR-mediated Signaling and Cardiac Function

Mammalian target of rapamycin (mTOR) is a key regulator for cell growth through modulating components of the translation machinery. Previously, numerous pharmacological studies using rapamycin suggested that mTOR has an important role in regulating cardiac hypertrophic growth. To further investigate...

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Bibliografiska uppgifter
Huvudupphovsmän: Shen, Wei-Hua, Chen, Zhuang, Shi, Shu, Chen, Hanying, Zhu, Wuqiang, Penner, Anne, Bu, Guixue, Li, Wei, Boyle, David W., Rubart, Michael, Field, Loren J., Abraham, Robert, Liechty, Edward A., Shou, Weinian
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Mechanisms of Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376248/
https://ncbi.nlm.nih.gov/pubmed/18326485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801510200
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