Cardiac Restricted Overexpression of Kinase-dead Mammalian Target of Rapamycin (mTOR) Mutant Impairs the mTOR-mediated Signaling and Cardiac Function

Mammalian target of rapamycin (mTOR) is a key regulator for cell growth through modulating components of the translation machinery. Previously, numerous pharmacological studies using rapamycin suggested that mTOR has an important role in regulating cardiac hypertrophic growth. To further investigate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shen, Wei-Hua, Chen, Zhuang, Shi, Shu, Chen, Hanying, Zhu, Wuqiang, Penner, Anne, Bu, Guixue, Li, Wei, Boyle, David W., Rubart, Michael, Field, Loren J., Abraham, Robert, Liechty, Edward A., Shou, Weinian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Mechanisms of Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376248/
https://ncbi.nlm.nih.gov/pubmed/18326485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801510200
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