Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy

The epidermal growth factor receptor (EGFR) is a validated target in squamous cell carcinoma (SCC) of the head and neck. Most patients, however, do not respond or develop resistance to this agent. Mammalian target of rapamycin (mTOR) is involved in the pathogenesis of SCC of the head and neck (SCCHN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jimeno, A, Kulesza, P, Wheelhouse, J, Chan, A, Zhang, X, Kincaid, E, Chen, R, Clark, D P, Forastiere, A, Hidalgo, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Translational Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360107/
https://ncbi.nlm.nih.gov/pubmed/17342092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603656
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