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Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy
The epidermal growth factor receptor (EGFR) is a validated target in squamous cell carcinoma (SCC) of the head and neck. Most patients, however, do not respond or develop resistance to this agent. Mammalian target of rapamycin (mTOR) is involved in the pathogenesis of SCC of the head and neck (SCCHN...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360107/ https://ncbi.nlm.nih.gov/pubmed/17342092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603656 |
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