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A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
Autosomal dominant polycystic kidney disease is an important cause of end-stage renal disease, for which there is no proven therapy1. Mutations in PKD1 (the gene encoding polycystin-1) are the principal cause of this disease. The disease begins in utero2 and is slowly progressive, but it is not know...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2302790/ https://ncbi.nlm.nih.gov/pubmed/17965720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1675 |
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