Pkd1 and Pkd2 Are Required for Normal Placental Development

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of inherited renal failure that results from mutations in PKD1 and PKD2. The disorder is characterized by focal cyst formation that involves somatic mutation of the wild type allele in a large fraction of cysts. Consi...

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Detalhes bibliográficos
Main Authors: Garcia-Gonzalez, Miguel A., Outeda, Patricia, Zhou, Qin, Zhou, Fang, Menezes, Luis F., Qian, Feng, Huso, David L., Germino, Gregory G., Piontek, Klaus B., Watnick, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940908/
https://ncbi.nlm.nih.gov/pubmed/20862291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012821
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