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A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

Autosomal dominant polycystic kidney disease is an important cause of end-stage renal disease, for which there is no proven therapy1. Mutations in PKD1 (the gene encoding polycystin-1) are the principal cause of this disease. The disease begins in utero2 and is slowly progressive, but it is not know...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piontek, Klaus, Menezes, Luis F, Garcia-Gonzalez, Miguel A, Huso, David L, Germino, Gregory G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2302790/
https://ncbi.nlm.nih.gov/pubmed/17965720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1675
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