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Polycystin Signaling is Required for Directed Endothelial Cell Migration and Lymphatic Development

Autosomal Dominant Polycystic Kidney Disease is a common form of inherited kidney disease that is caused by mutations in two genes, PKD1 (polycystin-1) and PKD2 (polycystin-2). Mice with germ line deletion of either gene die in mid gestation with a vascular phenotype that includes profound edema. Al...

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Detalhes bibliográficos
Main Authors: Outeda, Patricia, Huso, David L., Fisher, Steven A., Halushka, Marc K., Kim, Hyunho, Qian, Feng, Germino, Gregory G., Watnick, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040350/
https://ncbi.nlm.nih.gov/pubmed/24767998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.064
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