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Polycystin-1 Is Required for Stereocilia Structure But Not for Mechanotransduction in Inner Ear Hair Cells

The polycystic kidney disease-1 (Pkd1) gene encodes a large transmembrane protein (polycystin-1, or PC-1) that is reported to function as a fluid flow sensor in the kidney. As a member of the transient receptor potential family, PC-1 has also been hypothesized to play a role in the elusive mechanoel...

詳細記述

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書誌詳細
主要な著者: Steigelman, Katherine A., Lelli, Andrea, Wu, Xudong, Gao, Jiangang, Lin, Susan, Piontek, Klaus, Wodarczyk, Claas, Boletta, Alessandra, Kim, Hyunho, Qian, Feng, Germino, Gregory, Géléoc, Gwenaëlle S. G., Holt, Jeffrey R., Zuo, Jian
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164988/
https://ncbi.nlm.nih.gov/pubmed/21865467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6531-10.2011
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