TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear

Sensory transduction in auditory and vestibular hair cells requires expression of transmembrane channel-like (Tmc) 1 and 2 genes, but the function of these genes is unknown. To investigate the hypothesis that TMC1 and TMC2 proteins are components of the mechanosensitive ion channels that convert mec...

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Detalhes bibliográficos
Main Authors: Pan, Bifeng, Géléoc, Gwenaelle S., Asai, Yukako, Horwitz, Geoffrey C., Kurima, Kiyoto, Ishikawa, Kotaro, Kawashima, Yoshiyuki, Griffith, Andrew J., Holt, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827726/
https://ncbi.nlm.nih.gov/pubmed/23871232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.06.019
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