CD4 and Major Histocompatibility Complex Class I Downregulation by the Human Immunodeficiency Virus Type 1 Nef Protein in Pediatric AIDS Progression

The human immunodeficiency virus type 1 (HIV-1) nef gene is a crucial determinant in AIDS disease progression. Although several in vitro activities have been attributed to the Nef protein, identifying the one critical for in vivo pathogenicity remains elusive. In this study, we examined a large numb...

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Detalhes bibliográficos
Main Authors: Casartelli, Nicoletta, Di Matteo, Gigliola, Potestà, Marina, Rossi, Paolo, Doria, Margherita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC229262/
https://ncbi.nlm.nih.gov/pubmed/14557639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11536-11545.2003
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