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Human Immunodeficiency Virus Type 1 Nef Functions at the Level of Virus Entry by Enhancing Cytoplasmic Delivery of Virions

The Nef protein of the type 1 human immunodeficiency virus (HIV-1) plays a key although poorly understood role in accelerating the progression of clinical disease in vivo. Nef exerts several biological effects in vitro, including enhancement of virion infectivity, downregulation of CD4 and major his...

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Detalles Bibliográficos
Main Authors: Schaeffer, Evelyne, Geleziunas, Romas, Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC115925/
https://ncbi.nlm.nih.gov/pubmed/11222724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2993-3000.2001
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