Direct Binding of Human Immunodeficiency Virus Type 1 Nef to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail Disrupts MHC-I Trafficking

Nef, an essential pathogenic determinant for human immunodeficiency virus type 1, has multiple functions that include disruption of major histocompatibility complex class I molecules (MHC-I) and CD4 and CD28 cell surface expression. The effects of Nef on MHC-I have been shown to protect infected cel...

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Detalhes bibliográficos
Main Authors: Williams, Maya, Roeth, Jeremiah F., Kasper, Matthew R., Fleis, Rebekah I., Przybycin, Chris G., Collins, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136906/
https://ncbi.nlm.nih.gov/pubmed/12414957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12173-12184.2002
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