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Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

Recent evidence indicates that the nef gene of human immunodeficiency virus type 1 augments rather than inhibits viral replication in both cell culture and in vivo models. In addition, nef alters various normal cellular processes, including the display of CD4 on the cell surface. However, it remains...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Goldsmith, M A, Warmerdam, M T, Atchison, R E, Miller, M D, Greene, W C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4112-4121.1995
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