The Human Immunodeficiency Virus Type 1 nef Gene Can to a Large Extent Replace Simian Immunodeficiency Virus nef In Vivo

The nef gene of the pathogenic simian immunodeficiency virus (SIV) 239 clone was replaced with primary human immunodeficiency virus type 1 (HIV-1) nef alleles to investigate whether HIV-1 Nef can substitute for SIV Nef in vivo. Initially, two rhesus macaques were infected with the chimeric viruses (...

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Autores principales: Kirchhoff, Frank, Münch, Jan, Carl, Silke, Stolte, Nicole, Mätz-Rensing, Kerstin, Fuchs, Dietmar, Ten Haaft, Peter, Heeney, Jonathan L., Swigut, Tomek, Skowronski, Jacek, Stahl-Hennig, Christiane
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC112855/
https://ncbi.nlm.nih.gov/pubmed/10482588
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