The Human Immunodeficiency Virus Type 1 nef Gene Can to a Large Extent Replace Simian Immunodeficiency Virus nef In Vivo

The nef gene of the pathogenic simian immunodeficiency virus (SIV) 239 clone was replaced with primary human immunodeficiency virus type 1 (HIV-1) nef alleles to investigate whether HIV-1 Nef can substitute for SIV Nef in vivo. Initially, two rhesus macaques were infected with the chimeric viruses (...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Kirchhoff, Frank, Münch, Jan, Carl, Silke, Stolte, Nicole, Mätz-Rensing, Kerstin, Fuchs, Dietmar, Ten Haaft, Peter, Heeney, Jonathan L., Swigut, Tomek, Skowronski, Jacek, Stahl-Hennig, Christiane
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482588/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8371-8383.1999
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