CD4 and Major Histocompatibility Complex Class I Downregulation by the Human Immunodeficiency Virus Type 1 Nef Protein in Pediatric AIDS Progression

The human immunodeficiency virus type 1 (HIV-1) nef gene is a crucial determinant in AIDS disease progression. Although several in vitro activities have been attributed to the Nef protein, identifying the one critical for in vivo pathogenicity remains elusive. In this study, we examined a large numb...

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Vydáno v:	J Virol
Hlavní autoři:	Casartelli, Nicoletta, Di Matteo, Gigliola, Potestà, Marina, Rossi, Paolo, Doria, Margherita
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11536-11545.2003
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