CD4 and Major Histocompatibility Complex Class I Downregulation by the Human Immunodeficiency Virus Type 1 Nef Protein in Pediatric AIDS Progression

The human immunodeficiency virus type 1 (HIV-1) nef gene is a crucial determinant in AIDS disease progression. Although several in vitro activities have been attributed to the Nef protein, identifying the one critical for in vivo pathogenicity remains elusive. In this study, we examined a large numb...

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Pubblicato in:	J Virol
Autori principali:	Casartelli, Nicoletta, Di Matteo, Gigliola, Potestà, Marina, Rossi, Paolo, Doria, Margherita
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11536-11545.2003
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