CD4 and Major Histocompatibility Complex Class I Downregulation by the Human Immunodeficiency Virus Type 1 Nef Protein in Pediatric AIDS Progression

The human immunodeficiency virus type 1 (HIV-1) nef gene is a crucial determinant in AIDS disease progression. Although several in vitro activities have been attributed to the Nef protein, identifying the one critical for in vivo pathogenicity remains elusive. In this study, we examined a large numb...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Casartelli, Nicoletta, Di Matteo, Gigliola, Potestà, Marina, Rossi, Paolo, Doria, Margherita
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11536-11545.2003
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