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Comparison of BRCT domains of BRCA1 and 53BP1: A biophysical analysis
53BP1 interacts with the DNA-binding core domain of the tumor suppressor p53 and enhances p53-mediated transcriptional activation. The p53-binding region of 53BP1 maps to the C-terminal BRCT domains, which are homologous to those found in the breast cancer protein BRCA1 and in other proteins involve...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286730/ https://ncbi.nlm.nih.gov/pubmed/14978302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03461404 |
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