Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

The BRCT (BRCA1 C-terminus) is an evolutionary conserved protein–protein interacting module found as single, tandem or multiple repeats in a diverse range of proteins known to play roles in the DNA-damage response. The BRCT domains of 53BP1 bind to the tumour suppressor p53. To investigate the natur...

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Bibliografiske detaljer
Main Authors: Derbyshire, Dean J., Basu, Balaku P., Serpell, Louise C., Joo, Woo S., Date, Takayasu, Iwabuchi, Kuniyoshi, Doherty, Aidan J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC126127/
https://ncbi.nlm.nih.gov/pubmed/12110597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf383
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