RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1

Recruitment of RAD18 to stalled replication forks facilitates monoubiquitination of PCNA during S-phase, promoting translesion synthesis at sites of UV irradiation-induced DNA damage. In this study, we show that RAD18 is also recruited to ionizing radiation (IR)-induced sites of DNA double-strand br...

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Bibliografische gegevens
Hoofdauteurs: Watanabe, Kenji, Iwabuchi, Kuniyoshi, Sun, Jinghua, Tsuji, Yuri, Tani, Tokio, Tokunaga, Kazuaki, Date, Takayasu, Hashimoto, Mitsumasa, Yamaizumi, Masaru, Tateishi, Satoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673428/
https://ncbi.nlm.nih.gov/pubmed/19228710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp082
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