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Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52
In vertebrates, genomic DNA double-strand breaks (DSBs) are removed by non-homologous end-joining processes: classical non-homologous end-joining (c-NHEJ) and alternative end-joining (alt-EJ); or by homology-dependent processes: gene-conversion (GC) and single-strand annealing (SSA). Surprisingly, t...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7038941/ https://ncbi.nlm.nih.gov/pubmed/31832684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1167 |
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