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Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
Brca1 C-terminal (BRCT) domains are a common protein–protein interaction motif in proteins involved in the DNA damage response and DNA repair. The DNA-damage response protein 53BP1 has two BRCT domains that bind to the DNA-binding domain of p53. The 53BP1 tandem-BRCT region is homologous to the tand...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155350/ https://ncbi.nlm.nih.gov/pubmed/11877378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.959202 |
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