Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

Brca1 C-terminal (BRCT) domains are a common protein–protein interaction motif in proteins involved in the DNA damage response and DNA repair. The DNA-damage response protein 53BP1 has two BRCT domains that bind to the DNA-binding domain of p53. The 53BP1 tandem-BRCT region is homologous to the tand...

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Main Authors: Joo, Woo S., Jeffrey, Philip D., Cantor, Sharon B., Finnin, Michael S., Livingston, David M., Pavletich, Nikola P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155350/
https://ncbi.nlm.nih.gov/pubmed/11877378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.959202
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