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The Tandem BRCT Domain of 53BP1 Is Not Required for Its Repair Function
53BP1 plays an important role in cellular response to DNA damage. It is thought to be the mammalian homologue of budding yeast Rad9 and/or fission yeast Crb2. Rad9/Crb2 are bona fide checkpoint proteins whose activation requires their corresponding C-terminal tandem BRCT (BRCA1 C-terminal) motifs, w...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853281/ https://ncbi.nlm.nih.gov/pubmed/17043355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607577200 |
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