Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Histone lysine methylation has been linked to the recruitment of mammalian DNA repair factor 53BP1 and putative fission yeast homolog Crb2 to DNA double-strand breaks (DSBs), but how histone recognition is achieved has not been established. Here we demonstrate that this link occurs through direct bi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Botuyan, Maria Victoria, Lee, Joseph, Ward, Irene M., Kim, Ja-Eun, Thompson, James R., Chen, Junjie, Mer, Georges
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804291/
https://ncbi.nlm.nih.gov/pubmed/17190600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.10.043
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge