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Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S

Deacetylation of nucleosomes by the Rpd3S histone deacetylase along the path of transcribing RNA polymerase II regulates access to DNA, contributing to faithful gene transcription. The association of Rpd3S with chromatin requires its Eaf3 subunit, which binds histone H3 methylated at lysine 36 (H3K3...

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Detalhes bibliográficos
Main Authors: Xu, Chao, Cui, Gaofeng, Botuyan, Maria Victoria, Mer, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582589/
https://ncbi.nlm.nih.gov/pubmed/18818090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.08.008
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