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Histone H3 Lysine 36 Methylation Antagonizes Silencing in Saccharomyces cerevisiae Independently of the Rpd3S Histone Deacetylase Complex
In yeast, methylation of histone H3 on lysine 36 (H3-K36) is catalyzed by the NSD1 leukemia oncoprotein homolog Set2. The histone deacetylase complex Rpd3S is recruited to chromatin via binding of the chromodomain protein Eaf3 to methylated H3-K36 to prevent erroneous transcription initiation. Here...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Copyright © 2007 by the Genetics Society of America
2007
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800606/ https://ncbi.nlm.nih.gov/pubmed/17179083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.067751 |
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