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Histone H3 Lysine 36 Methylation Antagonizes Silencing in Saccharomyces cerevisiae Independently of the Rpd3S Histone Deacetylase Complex

In yeast, methylation of histone H3 on lysine 36 (H3-K36) is catalyzed by the NSD1 leukemia oncoprotein homolog Set2. The histone deacetylase complex Rpd3S is recruited to chromatin via binding of the chromodomain protein Eaf3 to methylated H3-K36 to prevent erroneous transcription initiation. Here...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tompa, Rachel, Madhani, Hiten D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Copyright © 2007 by the Genetics Society of America 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800606/
https://ncbi.nlm.nih.gov/pubmed/17179083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.067751
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