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The Rpd3-Sin3 Histone Deacetylase Regulates Replication Timing and Enables Intra-S Origin Control in Saccharomyces cerevisiae

The replication of eukaryotic genomes follows a temporally staged program, in which late origin firing often occurs within domains of altered chromatin structure(s) and silenced genes. Histone deacetylation functions in gene silencing in some late-replicating regions, prompting an investigation of t...

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Detalhes bibliográficos
Main Authors: Aparicio, Jennifer G., Viggiani, Christopher J., Gibson, Daniel G., Aparicio, Oscar M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416400/
https://ncbi.nlm.nih.gov/pubmed/15143171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4769-4780.2004
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