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The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase
In Saccharomyces cerevisiae, splicing of HAC1 mRNA is initiated in response to the accumulation of unfolded proteins in the endoplasmic reticulum by the transmembrane kinase-endoribonuclease Ire1p. Spliced Hac1p (Hac1(i)p) is a negative regulator of differentiation responses to nitrogen starvation,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419911/ https://ncbi.nlm.nih.gov/pubmed/15141165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600233 |
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