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The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase

In Saccharomyces cerevisiae, splicing of HAC1 mRNA is initiated in response to the accumulation of unfolded proteins in the endoplasmic reticulum by the transmembrane kinase-endoribonuclease Ire1p. Spliced Hac1p (Hac1(i)p) is a negative regulator of differentiation responses to nitrogen starvation,...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Schröder, Martin, Clark, Robert, Liu, Chuan Yin, Kaufman, Randal J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15141165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600233
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