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Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo

Eukaryotic organisms from yeast to human contain a multiprotein complex that includes Rpd3 histone deacetylase and Sin3 corepressor. The Sin3–Rpd3 complex, when recruited to promoters by specific DNA-binding proteins, can direct transcriptional repression of specific classes of target genes. It has...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kadosh, David, Struhl, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316629/
https://ncbi.nlm.nih.gov/pubmed/9512514
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