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Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo

Eukaryotic organisms from yeast to human contain a multiprotein complex that includes Rpd3 histone deacetylase and Sin3 corepressor. The Sin3–Rpd3 complex, when recruited to promoters by specific DNA-binding proteins, can direct transcriptional repression of specific classes of target genes. It has...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Kadosh, David, Struhl, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316629/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.6.797
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