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GSK3β is a negative regulator of platelet function and thrombosis
Glycogen synthase kinase (GSK)3β is a ser-thr kinase that is phosphorylated by the kinase Akt. Although Akt has been shown to regulate platelet function and arterial thrombosis, its effectors in platelets remain unknown. We show here that agonist-dependent phosphorylation of GSK3β in platelets is Ak...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275019/ https://ncbi.nlm.nih.gov/pubmed/18218855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111518 |
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