UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin αIIbβ3

UV-C irradiation has been shown to be effective for pathogen reduction in platelet concentrates, but preliminary work indicated that UV-C irradiation of platelets can induce platelet aggregation. In this study, the mechanism underlying this phenomenon was investigated. Irradiation of platelets with...

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Detalhes bibliográficos
Main Authors: Verhaar, Robin, Dekkers, David W. C., De Cuyper, Iris M., Ginsberg, Mark H., de Korte, Dirk, Verhoeven, Arthur J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597600/
https://ncbi.nlm.nih.gov/pubmed/18796633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-151043
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