The small GTPase Rap1b regulates the cross talk between platelet integrin α(2)β(1) and integrin α(IIb)β(3)

The involvement of the small GTPase Rap1b in platelet integrin α(2)β(1)-dependent outside-in signaling was investigated. Platelet adhesion to 4 different specific ligands for integrin α(2)β(1), monomeric collagen, decorin, and collagen-derived peptides CB8(II) and CB11(II), induced a robust and rapi...

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Detalhes bibliográficos
Main Authors: Bernardi, Bruno, Guidetti, Gianni F., Campus, Francesca, Crittenden, Jill R., Graybiel, Ann M., Balduini, Cesare, Torti, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895386/
https://ncbi.nlm.nih.gov/pubmed/16357324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-3023
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