Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets

Kindlin-3, a protein 4.1, ezrin, radixin, and moesin (FERM) domain–containing adaptor in hematopoietic cells, is essentially required for supporting the bidirectional integrin αIIbβ3 signaling in platelets by binding to the integrin β3 cytoplasmic tail. However, the structural details of kindlin-3’s...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Sun, Jiaojiao, Xiao, Desheng, Ni, Yuan, Zhang, Tianlong, Cao, Zhongyuan, Xu, Zhou, Nguyen, Huong, Zhang, Jun, White, Gilbert C., Ding, Jianping, Ma, Yan-Qing, Xu, Zhen
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Thrombosis and Hemostasis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362375/
https://ncbi.nlm.nih.gov/pubmed/32649767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001575
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