Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets

Kindlin-3, a protein 4.1, ezrin, radixin, and moesin (FERM) domain–containing adaptor in hematopoietic cells, is essentially required for supporting the bidirectional integrin αIIbβ3 signaling in platelets by binding to the integrin β3 cytoplasmic tail. However, the structural details of kindlin-3’s...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Sun, Jiaojiao, Xiao, Desheng, Ni, Yuan, Zhang, Tianlong, Cao, Zhongyuan, Xu, Zhou, Nguyen, Huong, Zhang, Jun, White, Gilbert C., Ding, Jianping, Ma, Yan-Qing, Xu, Zhen
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362375/
https://ncbi.nlm.nih.gov/pubmed/32649767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001575
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