Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets

Kindlin-3, a protein 4.1, ezrin, radixin, and moesin (FERM) domain–containing adaptor in hematopoietic cells, is essentially required for supporting the bidirectional integrin αIIbβ3 signaling in platelets by binding to the integrin β3 cytoplasmic tail. However, the structural details of kindlin-3’s...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Sun, Jiaojiao, Xiao, Desheng, Ni, Yuan, Zhang, Tianlong, Cao, Zhongyuan, Xu, Zhou, Nguyen, Huong, Zhang, Jun, White, Gilbert C., Ding, Jianping, Ma, Yan-Qing, Xu, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362375/
https://ncbi.nlm.nih.gov/pubmed/32649767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001575
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