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Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets
Kindlin-3, a protein 4.1, ezrin, radixin, and moesin (FERM) domain–containing adaptor in hematopoietic cells, is essentially required for supporting the bidirectional integrin αIIbβ3 signaling in platelets by binding to the integrin β3 cytoplasmic tail. However, the structural details of kindlin-3’s...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362375/ https://ncbi.nlm.nih.gov/pubmed/32649767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001575 |
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