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Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice
Serglycin (SG), the hematopoietic cell secretory granule proteoglycan, is crucial for storage of specific secretory proteins in mast cells, neutrophils, and cytotoxic T lymphocytes. We addressed the role of SG in platelets using SG(−/−) mice. Wild-type (WT) but not SG(−/−) platelets contained chondr...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275015/ https://ncbi.nlm.nih.gov/pubmed/18094327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-104703 |
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