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Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells
The mechanisms that govern whether a cell dies by apoptosis or necrosis are not fully understood. Here we show that serglycin, a secretory granule proteoglycan of hematopoietic cells, can have a major impact on this decision. Wild type and serglycin(−/−) mast cells were equally sensitive to a range...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365731/ https://ncbi.nlm.nih.gov/pubmed/22493512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344796 |
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