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Proteolytic Histone Modification by Mast Cell Tryptase, a Serglycin Proteoglycan-dependent Secretory Granule Protease

A hallmark feature of mast cells is their high content of cytoplasmic secretory granules filled with various preformed compounds, including proteases of tryptase-, chymase-, and carboxypeptidase A3 type that are electrostatically bound to serglycin proteoglycan. Apart from participating in extracell...

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Autori principali: Melo, Fabio R., Vita, Francesca, Berent-Maoz, Beata, Levi-Schaffer, Francesca, Zabucchi, Giuliano, Pejler, Gunnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953279/
https://ncbi.nlm.nih.gov/pubmed/24478313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546895
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