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Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice
Serglycin (SG), the hematopoietic cell secretory granule proteoglycan, is crucial for storage of specific secretory proteins in mast cells, neutrophils, and cytotoxic T lymphocytes. We addressed the role of SG in platelets using SG(−/−) mice. Wild-type (WT) but not SG(−/−) platelets contained chondr...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275015/ https://ncbi.nlm.nih.gov/pubmed/18094327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-104703 |
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